Micronutrient fertilization enhances ROS scavenging system for alleviation of abiotic stresses in plants.

Reactive oxygen species (ROS) such as hydrogen peroxide at low concentrations act as signaling of several abiotic stresses. Overproduction of hydrogen peroxide causes the oxidation of plant cell lipid phosphate layer promoting senescence and cell death. To mitigate the effect of ROS, plants develop antioxidant defense mechanisms (superoxide dismutase, catalase, guaiacol peroxidase), ascorbate-glutathione cycle enzymes (ASA-GSH) (ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase and glutathione reductase), which have the function of removing and transforming ROS into non-toxic substances to maintain cellular homeostasis. Foliar or soil application of fertilizers containing B, Cu, Fe, Mn, Mo, Ni, Se and Zn at low concentrations has the ability to elicit and activate antioxidative enzymes, non-oxidizing metabolism, as well as sugar metabolism to mitigate damage by oxidative stress. Plants treated with micronutrients show higher tolerance to abiotic stress and better nutritional status. In this review, we summarized results indicating micronutrient actions in order to reduce ROS resulting the increase of photosynthetic capacity of plants for greater crop yield. This meta-analysis provides information on the mechanism of action of micronutrients in combating ROS, which can make plants more tolerant to several types of abiotic stress such as extreme temperatures, salinity, heavy metals and excess light.

Comparison of pressure pain threshold between muscles in the contracted and relaxed state in patients with myofascial pain: a cross-sectional study.

OBJECTIVE: The aim of this study was to compare the Pressure Pain Threshold (PPT) of the masseter and temporal muscles in the contracted and relaxed state between patients with myofascial pain (MFP) and asymptomatic individuals. MATERIALS AND METHODS: Were included 40 women divided into two groups: test group - 20 individuals with MFP; control group - 20 asymptomatic individuals. The PPT was measured using a digital algometer. First. PPT was obtained with the relaxed muscles and soon after with the contracted muscles. To compare the mean value of the PPT of each muscle between the groups the independent Student's t-test was used. To compare the means value of the PPT between contracted and relaxed musculature within each group, the Paired Student's t-test was used. All the tests were conducted with a 5% significance level. RESULTS: Patients in Test group presented lower mean PPT values in relation to Control group (p<0.05). There was an increase in the mean PPT values with contracted muscles, but this increase was not statistically significant (p>0.05). CONCLUSION: Patients with MFP present lower PPT than asymptomatic individuals. Muscle contraction was able to increase PPT in relation to relaxed muscles, but not in a statistically significant way.

Cicatrizadores personalizados: relato de caso / Customized healing abutments: case report

Quando feita a instalação de um implante imediato pode se optar entre a instalação de uma coroa provisória clínica, um cicatrizador ou pode se optar pelo fechamento do implante para um tratamento em duas etapas cirúrgicas. O uso de cicatrizadores personalizados sela os implantes e leva a uma cicatrização individualizada, que favorece a confecção das coroas subsequentes. O presente trabalho objetiva relatar um caso clínico envolvendo um implante imediato e a instalação de um cicatrizador personalizado, demonstrando os resultados e a importância de conhecimento dessa técnica pelo cirurgião-dentista.

When installing an immediate implant, you can choose between installing a temporary clinical crown, healing abutments, or to close the implant for a two-step surgical treatment. The use of customized healing abutments seals the implants and leads to individualized healing, which favors the creation of subsequent crowns. The present study aims to report a clinical case involving an immediate implant and the installation of customized healing abutments, demonstrating the results and the importance of knowledge of this technique by the dentist.

Is migraine a complicating factor for evidence-based therapy for masticatory myofascial pain? A case-control study.

OBJECTIVE: This study aimed to assess the response to conservative treatment of pain in patients diagnosed with masticatory myofascial pain (MMP) with or without migraine. STUDY DESIGN: A total of 61 patients were evaluated and divided into 2 groups: Group 1 (G1), patients with MMP (n = 34); Group 2 (G2), patients with MMP and migraine (n = 27). Pain was assessed subjectively by visual analog scale (VAS) and objectively through masticatory muscle palpation at baseline and after 3 treatment visits. Treatment included occlusal appliances, medication, and self-care exercises. RESULTS: G2 reported greater discomfort subjectively and objectively at all evaluation visits; however, significant difference between groups was noted objectively only at baseline (P = .0052). Regardless of group, pain levels decreased significantly over time as measured by VAS analyses (G1 P = .0033; G2 P = .0031) and muscle palpation (G1 P < .0001; G2 P < .0001). CONCLUSIONS: Evidence-based therapy improved pain scores over time in MMP patients regardless of the presence of migraine.

Evaluation of dry needling and 0.5% lidocaine injection therapies in myofascial pain trigger points in masticatory muscles

OBJECTIVE: The purpose of this study was to compare the effectiveness of trigger points injections using lidocaine 0.5% and dry needling without any kind of home-based rehabilitation program. METHODS: Sixteen patients with myofascial pain and trigger points in masticatory muscles were randomly assigned to two groups and received only one application session. The pressure pain threshold (PPT) was recorded before and after the injection: Ten minutes, 24 hours later, 7, 15, 21 and 30 days after the treatment. Visual analogue scale (VAS) was used to in all evaluation periods. RESULTS: There were no difference between groups for PPT, but for all groups the PPT during the time significantly increased when compared the before treatment. VAS showed differences between groups and during the time. The 0.5% lidocaine had the lowest VAS values when compared to dry needling, but at 30 days there were no differences among them. CONCLUSIONS: Despite the differences in VAS and considering there were no differences in PPT increases, we concluded that, in this study, both groups were able to disrupt the mechanisms of trigger point and relieve the myofascial pain symptoms.

Estudo do impacto da enxaqueca na severidade da dor miofascial da musculatura mastigatória / Muscle pain intensity of patients with myofascial pain with different additional diagnoses

OBJETIVO: comparar a severidade da dor subjetiva e objetiva, além de outras características associadas entre pacientes com dor miofascial com e sem o diagnóstico adicional de enxaqueca. MÉTODOS: foram selecionados 203 pacientes, com idade média de 40,3 anos (89,2 por cento do sexo feminino), que se apresentaram à Clínica de Dor Orofacial da Universidade da Califórnia, Los Angeles, EUA - todos com diagnóstico primário de dor miofascial. Pacientes com diagnóstico secundário de enxaqueca foram incluídos (n=83) e formaram o grupo 2. O teste de Mann-Whitney foi utilizado para comparar o grupo 1 (dor miofascial) com o 2 (dor miofascial + enxaqueca) quanto à intensidade de dor à palpação e subjetiva, através de Escalas Analógicas Visuais (EAV). Também com o auxílio de EAV, foram comparados estado de humor, problemas com a função, qualidade do sono e incapacidade. Em todos os testes foi adotado um nível de significância de 5 por cento. RESULTADOS: o grupo 2 apresentou níveis de dor à palpação muscular estatisticamente maiores que o grupo 1 (p<0,05). Ao se analisar a intensidade de dor subjetiva obtida através da EAV, o grupo 2 apresentou níveis maiores de dor subjetiva (EAV) em todas as medições, com significância estatística para "dor no momento" e "dor máxima" (p<0,05). Da mesma maneira, o grupo 2 mostrou níveis maiores, obtidos através da EAV, de problemas com humor, incapacidade, problemas com a função mandibular e problemas com sono/descanso, sendo que apenas o último apresentou significância estatística (p<0,05). CONCLUSÕES: a comorbidade enxaqueca exerce forte impacto na severidade da dor e na qualidade de vida de pacientes que apresentam diagnóstico primário de dor miofascial.

OBJECTIVES: To compare subjective and objective pain intensity and associated characteristics in myofascial pain (MFP) patients with and without migraine. METHODS: The sample was comprised by 203 consecutive patients, mean age of 40.3 (89.2 percent of females), primarily diagnosed with MFP, who presented to the UCLA Orofacial Pain Clinic. Patients with secondary diagnosis of migraine (n=83) were included and comprised group 2. In order to compare group 1 (MFP) with group 2 (MFP + migraine) regarding objective pain (palpation scores) and subjective by means of visual analog scales (VAS) pain levels. Also, comparisons of mood problems, jaw function problems, sleep quality and disability levels using VAS were performed using the Mann-Whitney test. A significance level of 5 percent was adopted. RESULTS: Mann-Whitney test revealed that group 2 presented significantly higher pain levels on palpation of masticatory and cervical muscles in comparison to group 1 (p<0.05). Group 2 also presented higher levels of subjective pain, with statistical significance for "pain at the moment" and "highest pain" (p<0.05). Additionally, group 2 showed higher levels of mood problems, disability, jaw function impairment and sleep problems than group 1 with statistical significance for the later (p<0.05). CONCLUSIONS: Migraine comorbidity demonstrated a significant impact on pain intensity and life quality of patients with MFP. Clinicians should approach both conditions in order to achieve better treatment outcomes.

Effect of experimental chewing on masticatory muscle pain onset.

OBJECTIVES: To evaluate the effect of a chewing exercise on pain intensity and pressure-pain threshold in patients with myofascial pain. METHODS: Twenty-nine consecutive women diagnosed with myofascial pain (MFP) according to the Research Diagnostic Criteria comprised the experimental group and 15 healthy age-matched female were used as controls. Subjects were asked to chew a gum stick for 9 min and to stay at rest for another 9 min afterwards. Pain intensity was rated on a visual analog scale (VAS) every 3 min. At 0, 9 and 18 min, the pressure-pain threshold (PPT) was measured bilaterally on the masseter and the anterior, medium, and posterior temporalis muscles. RESULTS: Patients with myofascial pain reported increase (76%) and no change (24%) on the pain intensity measured with the VAS. A reduction of the PPT at all muscular sites after the exercise and a non-significant recovery after rest were also observed. CONCLUSION: The following conclusions can be drawn: 1. there are at least two subtypes of patients with myofascial pain that respond differently to experimental chewing; 2. the chewing protocol had an adequate discriminative ability in distinguishing patients with myofascial pain from healthy controls.

Effect of experimental chewing on masticatory muscle pain onset

OBJECTIVES: To evaluate the effect of a chewing exercise on pain intensity and pressure-pain threshold in patients with myofascial pain. METHODS: Twenty-nine consecutive women diagnosed with myofascial pain (MFP) according to the Research Diagnostic Criteria comprised the experimental group and 15 healthy age-matched female were used as controls. Subjects were asked to chew a gum stick for 9 min and to stay at rest for another 9 min afterwards. Pain intensity was rated on a visual analog scale (VAS) every 3 min. At 0, 9 and 18 min, the pressure-pain threshold (PPT) was measured bilaterally on the masseter and the anterior, medium, and posterior temporalis muscles. RESULTS: Patients with myofascial pain reported increase (76 percent) and no change (24 percent) on the pain intensity measured with the VAS. A reduction of the PPT at all muscular sites after the exercise and a non-significant recovery after rest were also observed. CONCLUSION: The following conclusions can be drawn: 1. there are at least two subtypes of patients with myofascial pain that respond differently to experimental chewing; 2. the chewing protocol had an adequate discriminative ability in distinguishing patients with myofascial pain from healthy controls.

O papel do fator oclusal no sucesso das próteses implantossuportadas: uma análise crítica / The role of occlusal factor in the success of the implant-supported prostheses: a critical analysis

As reabilitações protéticas sobre implantes têm revolucionado o tratamento dos pacientes parcial ou totalmente desdentados. No entanto, alguns cuidados, principalmente em relação ao planejamento, são imprescindíveis para uma resolução estética e funcional satisfatória em curto e longo prazo.

Quantidade de pressão e padrão de dor referida em pacientes portadores de dor miofascial / Pressure pain treshold and referred pain pattern in myofascial pain patients

Os propósitos deste estudo foram: determinar a quantidade de pressão que estimulasse resposta dolorosaem pacientes com pontos gatilho (PG) quando comparado ao grupo controle assintomático; determinar umintervalo de tempo de manutenção de pressão para que houvesse o surgimento do processo de dor referida(DR) e verificar o padrão de DR provocada. Selecionou-se 24 pacientes portadores de dor miofascial e parao grupo controle, 20 indivíduos livres de qualquer sintomatologia de disfunção temporomandibular. Ambos os grupos foram examinados por um único examinador em pontos gatilho previamente diagnosticados. Noitem quantidade de pressão, o intervalo no grupo portador de dor miofascial foi significantemente menor queo grupo controle. O padrão de DR obtido confere com aquele descrito na literatura. Os autores deste estudoconcluíram que o limiar de dor a palpação em portadores de dor miofascial é menor que em indivíduos nãoportadores e o padrão da manifestação de DR semelhante ao descrito na literatura.

The purposes of this study were: to determine the amount of pressure necessary to create painful responsein patients with myofascial pain in head and neck when compared with a assintomatic control group; to determineone sustained pressure time that causes referred pain and to determine the referred pain pattern whenthe trigger points were stimulated. The group A was formed by 24 patients who had myofascial pain, andgroup B was composed by 20 myofascial pain free subjects. For both groups, examination was performed byonly an experienced and trained professional. Group A had lower pressure pain threshold when comparedwith group B.( p < 0,01) The referred pain patterns was very similar to those described in literature. It wasconcluded that the pressure pain threshold in myofascial pain patients is lower than pressure pain thresholdin non-patients.

Palpação muscular: sensibilidade e especificidade / Muscle palpation: sensitivity and specificity

Este trabalho se propõe a analisar critérios de sensibilidade e especificidade relativos à palpação muscular, exame largamente utilizado na abordagem das Disfunções Temporomandibulares. Baseado na literatura pertinente, procurou-se abordar e discutir os aspectos importantes desse exame, as controvérsias existentes, com ênfase na sensibilidade e especificidade, características tão pouco compreendidas, evitando, assim, diagnósticos equivocados e execução de tratamentos desnecessários

O uso da energia de Microondas na polimerização das bases acrílicas em Prótese Total. Técnica de processamento / Use of microwave energy polymerization of base acrylic in complete denture. Tchnique of process

A técnica de poliemarização por microondas da resina acrílica para base de dentaduras foi submetida a diversos experimentos analisando suas qualidades e possibilidades de uso clínico, o correndo algumas conclusões contraditórias, talvez pelo fato de não se estabelecerem os mesmos critérios experimentais com: Forno de microondas, quantidade e tipo de amostragem. Mesmo assim, de maneira geral, o uso da energia de microondas é viável clinicamente